The mercury connection to eczema, autism, schizophrenia, lupus, asthma, and allergies( snipped from larger study) Bernard Windham- Chemical Engineer

The incidence of allergic and immune reactive conditions such as allergies, asthma, eczema, lupus, psoriasis, oral lichen planus, autism, etc. have been increasing rapidly in recent years(1,2,2b,3,23). According to the U.S. FDA, at least 26 million have allergies and at least 17 million have asthma. The largest increase has been in infants(1,2,2b,6,7,23), with an increase in autism cases of over 250% to over 500,000 (2,23,22), a level of almost 1 per 300 infants in the last decade(2), and over 10 % of infants- approximately 15 million in the U.S. with systemic eczema(1). Studies researching the reason for these rapid increases in infant reactive conditions seem to implicate earlier and higher usage of vaccines containing mercury(thimerosal) as a likely connection(2,2b,23,30,34). It has been estimated that if all of the vaccines reccomended by the American Assoc. of Pediatrics are given and contain thimerosal, then by age 6 monts an infant would have received 187 micrograms of ethylmercury which is more than the EPA health standard for organic mercury(33) and by age 3 the typical child has recieved over 235 micrograms of mercury thimerosal from vaccinations which is considerably more than Federal mercury safety guidelines, in addition to significant levels from other sources for many(23). Infants during this period have undeveloped blood brain barriers and much of the mercury goes to the brain, resulting in significant adverse neurological effects in those that are most susceptable. Many thousands of parents have reported that their child got such conditions after vaccination, and tests have confirmed high levels of mercury in manny of those tested, along with other toxic exposures. Many of those diagnosed with high mercury levels have also been found to have significant improvement after mercury detoxification(23,30,34,11). Thimerosal had been previously removed from similar preservative uses in eye drops and eye medications after evidence of a connection to chronic degenerative eye conditions. After over 15,000 law suits were filed in France over adverse effects of the Hepatitis B vaccine, the French Minister of Health ended the mandantory hepatitis B vaccination program for all school children. Adverse effects included neurological disorders and autoimmune disorders such as multiple sclerosis and lupus. Some hospitals in the U.S. also quit recommending certain vaccinations.

Studies have found mercury causes increased levels of the CD8 T-cytotoxic-suppressors(29). As noted previously, such populations of patients have also been found to have high levels of mercury and to recover after mercury detox(23,11,22,30,34). As mercury levels are reduced the protein binding is reduced and improvement in the enzymatic process occurs(22,11). Additional cellular level enzymatic effects of mercury’s binding with proteins include blockage of sulfur oxidation processes(18), enzymatic processes involving vitimins B6 and B12, effects on the cytochrome-C energy processes, along with mercury’s adverse effects on cellular mineral levels of calcium, magnesium, zinc, and lithium(22). Another of the results of these toxic exposures is the effect on the liver and disfunction of the liver detoxification processes which austistic children have been found to have(30,22). All of the austistic cases tested were found to have high toxic exposures/effects and liver detoxification profiles outside of normal.

(c) Gary Null, Second Opinion: Vaccinations, Gary Null and Associates,Inc., 2000.

(3) Silhan P, Arenberger P. Standard epicutaneous tests in ambulatory care of patients. Cas Lek Cesk 1999, 138(15):469-73.

(4) Reichrtova E et al, "Cord Serum Immunoglobulin E Related to Enviornmental Contamination of Human Placentas with Oganochlorine Compounds", Envir Health Perspec, 1999, 107(11):895-99; & Gavett SH et al. Residual Oil Fly Ash Amplifies Allergic Cytokines, Airway Responsiveness, and Inflamtion in Mice. Am J Respir Crit Care Med, 1999, 160(6):1897-1904; & Kramer U et al, Traffic- related air pollution is associated with atopy in children living in urban areas. Epidemiology 2000, 11(1): 64-70.

(5) Romaguera C, Vilaplana J. Contact dermatitis in children: 6 years experience. Contact Dermatitis 1998; 39(6): 277-80.

(6) Brasch J, Geier J, Schnuch A. Differentiiated contact allergy lists serve in quality improvement. Hautarzt 1998; 49(3): 184-91.

(7) Manzini BM, Ferdani G, Simonetti V, Donini M, Sedernari S. Contact senstization in children. Pediatr Dermatol 1998; 15(1): 12-17.

(8) Sun CC. Allergic contact dermatitis of the face from contact with nickel and ammoniated mercury. Contact Dermatitis 1987, 17(5):306-9.

(9) Xue C, He Z, Zhang H, Li S. Study on the contact allergen in patients with dermatitis and eczema. Wei Sheng Yen Chiu 1997, 26(5): 296-8.

(10) Aberer W, Holub H, Strohal R, Slavicek R. Palladium in dental alloys- the dermatologists responsibility to warn? Contact Dermatitis 1993. 28(3): 163-5.

(11) V.D.M.Stejskal, Dept. Of Clinical Chemistry, Karolinska Institute, Stockholm, Sweden LYMPHOCYTE IMMUNO-STIMULATION ASSAY -MELISA" & "Mercury-specific Lymphocytes: an indication of mercury allergy in man", J. Of Clinical Immunology, 1996, Vol 16(1);31-40; & VDM Stejskal et al, "MELISA: tool for the study of metal allergy", Toxicology in Vitro, 8(5):991-1000, 1994. see: http://www.melisa.org

(12) Sterzl I, Prochazkova J, Stejaskal VDM et al, Mercury and nickel allergy: risk facotrs in fatigue and autoimmunity. Neuroendocrinology Letters 1999; 20:221-228; & V.Stejskal, "MELISA: A New Technology for Diagnosing and Monitoring of Metal Sensitivity", Proceedings: 33rd Annual Meeting of American Acadamy of Environmental Medicine, Nov. 1998, Baltimore, Maryland.

(13) Redhe O, Pleva J. Recovery from asthma, allergies,ALS after removal of dental amalgam fillings. Int J of Risk & Safety in Medicine 1994; 4:229-236.

(15) Tejwani GA, Hanissian SH. Modulation of mu, delta, and kappa opioid receptors in rat brain by metal ions and histidine. Neuropharmology 1990; 29(5): 445-52.

(16) Mondal MS, Mitra S. Inhibition of bovine xanthine oxidase activity by Hg2+ and other metal ions. J Inorg Biochem 1996; 62(4): 271-9.

(17) Sastry KV, Gupta PK. In vitro inhibition of degestive enzymes by heavy metals and their reversal by chelating agents: Part 1, mercuric chloride intoxication. Bull Environ Contam Toxicol 1978; 20(6): 729-35; & W.Y.Boadi et al, Dept. Of Food Engineering and Biotechnology, T-I Inst of Tech., Haifa, Israel, "In vitro effect of mercury on enzyme activities", Environ Res, 1992, 57(1):96-106

(18) Mc Fadden SA, Phenotypic variation in xenobitic metabolish and adverse environmental response: focus on sulfur-dependent detoxification pathways. Toxicology, 1996, 111(1-3):43-65; & Markovich et al, "Heavy metals (Hg,Cd) inhibit the activity of the liver and kidney sulfate transporter Sat-1", Toxicol Appl Pharmacol, 1999,154(2):181-7; & Matts RL, Schatz JR, Hurst R, Kagen R. Toxic heavy metal ions inhibit reduction of disulfid bonds. J Biol Chem 1991; 266(19): 12695-702

(19) Puschel G, Mentlein R, Heymann E, 'Isolation and characterization of dipeptidyl peptidase IV from human placenta', Eur J Biochem 1982 Aug;126(2):359-65; & Kar NC, Pearson CM. Dipeptyl Peptidases in human muscle disease. Clin Chim Acta 1978; 82(1-2): 185-92.

(20) Stefanovic V. et al, Kidney ectopeptidases in mercuric chloride-induced renal failure. Cell Physiol Biochem 1998; 8(5): 278-84.

(21) Crinnion WJ. Environmental toxins and their common health effects. Altern Med Rev 2000, 5(1):52-63.

(22) Windham, B. Annotated Bibliography: Adverse health effects related to mercury and amalgam fillings and

clinically documented recoveries after amalgam replacement. (over 600 references); berniew1@earthlink.net

(23) Autism: a unique form of mercury poisoning. http://www.canfoundation.org/newcansite/sciwatch/invest.html

(24) J.R. Cade et al, Autism and schizophrenia linked to malfunctioning enzyme for milk protein digestion. Autism, Mar 1999. http://www.hsc.ufl.edu/post/post0399/post03_19/1.html

(25) Reichelt KL. Biochemistry and psycholphisiology of autistic syndromes. Tidsskr Nor Laegeforen 1994, 114(12):

1432-4; & Reichelt KL et al, Biologically active peptide-containing fractions in schizophrenia and childhood autism. Adv Biochem Psychopharmocol 1981; 28: 627-43; Lucarelli S, Cardi E, et al, Food allergy and infantile autism. Panminerva Med 1995; 37(3):137-41.

(26) Huebner FR, Lieberman KW, Rubino RP, Wall JS. Demonstration of high opioid-like activity in isolated peptides from wheat gluten hydrolysates. Peptides 1984; 5(6):1139-47.

(27) Willemsen-Swinkels SH, Buitelaar JK, Weijnen FG, Thisjssen JH, Van Engeland H. Plasma beta-endorphin concentrations in people with learning disbility and self-injurious and/or autisitic behavior. Br J Psychiary 1996; 168(1): 105-9; & Leboyer M, Launay JM et al. Difference between plasma N- and C-terminally directed beta-endorphin immunoreactivity in infantile autism. Am J Psychiatry 1994; 151(12): 1797-1801.

(28) Scifo R, Marchetti B, et al. Opioid-immune interactions in autism: behavioral and immunological assessment during a double-blind treatment with naltexone. Ann Ist Super Sanita 1996; 32(3): 351-9.

(30) Edelson SB, Cantor DS. Autism: xenobiotic influences. Toxicol Ind Health 1998; 14(4): 553-63; &

Liska, DJ. The detoxification enzyme systems. Altern Med Rev 1998. 3(3):187-98.

.(31) Sayers LG; Brown GR; Michell RH; Michelangeli F. The effec ts of thimerosal on calcium uptake and inositol1,4,5-trisphosphate-induced calcium release in cerebellar microsomes. Biochem J 1993 Feb 1;289

(33) Halsey, NA. Limiting Infant Exposure to Thimerosal in vaccines. J. of the Amer. Medical Assoc., 282: 1763-66.