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Jonathan Campbell, Health
Consultant |
| Let thy food be thy medicine,
and thy medicine be thy food. Hippocrates, Father of Medicine, 400 B.C. |
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Helping people take charge of their health |
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The Six Stages of Cardiovascular Disease
It has taken decades to find the train of events that cause the progression of cardiovascular disease. The most recent research was completed in 2010, but it has not been integrated into medical practice, literature, or any popular literature. (Important Note: most people and most doctors, including cardio doctors, do not know about the root cause of cardiovascular disease, a rather sad state of affairs. They still think it is caused by "LDL cholesterol." It isn't. ) Here is the chain of events, presented in a form that is understandable. Please note that not all of the stages appear in all cases; sometimes stages 3-5 are not prominent, though cardiovascular disease is quietly progressing. This process begins at birth. In extreme cases, such as profound ascorbate deficiency from birth, the resulting hemorrhage can result in high rates of infant mortality - Sudden Infant Death Syndrome. Stage 1- Vitamin Deficiency. Ascorbate (vitamin C) deficiency (which is almost universal in humans, worldwide) leads to inability of connective tissue cells (collagen) to self-repair from every day wear and tear and from microscopic holes created by white blood cells drilling their way through arteries to reach bacteria. If these sites are not healed or patched, we will hemorrhage – we’ll bleed to death internally. The normal collagen repair process requires vitamin C and two amino acids – lysine and proline. (As a side note: excess glucose caused by eating dietary sugars competes with vitamin C, causing even more deficiency.) Stage 2 - Inflammation. The sites of this disrepair signal the manufacture of an inflammatory chemical called IL-6 (Interleukene-6), which in turn signals the production of lipoprotein(a), a sticky compound otherwise known as cardiovascular plaque, which our bodies use as a temporary band-aid to prevent hemorrhage. Lipoprotein(a) is deposited throughout the arterial system and the presence of IL-6 causes insulin resistance.. Stage 3 - Insulin Resistance and Hypertension. The process inhibits insulin reactivity. That is, cells become less able to turn glucose into energy because their insulin receptor is inhibited by IL-6. This is called insulin resistance. Meanwhile, cells are still sending signals to the pancreas to produce more insulin to invoke their (inhibited) glucose-to-energy systems. This leads to hyperinsulinism – literally producing too much insulin. This in turn causes uncontrollable weight gain, as a result of excess insulin signaling fat cells to convert blood glucose into glycogen (and then into fat). At the same time, arterial deposits of lipoprotein narrow the arteries, causing hypertension (high blood pressure). Stage 4 – Severe Hypoglycemia. Excess insulin periodically rapidly depletes blood glucose, causing periodic severe hypoglycemia – literally insulin shock. This is life-threatening because many life-sustaining organs and cellular processes require blood glucose. Meanwhile, because insulin resistance becomes has become severe, cells needing glucose for energy production cannot get enough and are continually signaling for more insulin. The combination of excess insulin, periodic glucose depletion, lipoprotein(a) plaque accumulation and resultant reduced blood flow in small arteries results in further weight gain, increased blood pressure, cellular nutrient depletion, fatigue, depression, hair loss, spontaneous skin lesions, chronic and acute psoriasis, slow healing of wounds, decreased immunity, susceptibility to colds and flu, and generalized whole-body degeneration. Stage 5 – Type II Diabetes. The symptoms of Stage 4 accelerate. If the process is not stopped blood sugar levels become very difficult to control. In some cases the pancreas becomes so overworked that some pancreatic cells become inoperative and blood sugar increases without control. This is advanced Type II diabetes. Blood sugar interferes with vitamin C metabolism, accelerating lipoprotein(a) (cardiovascular plaque) accumulation leading to complete blockage of capillaries and small arteries, causing diabetic neuropathy and retinopathy. Stage 6. The build-up of lipoprotein(a) eventually clogs small and large arteries in the heart, brain, lungs, etc. – acute cardiovascular disease – leading to heart attack or stroke. The Pauling/Rath cardiovascular regimen, described here, stops and reverses this process, and it is the only known regimen that is proven to do so. However, the amounts specified should be modified by body weight, using 160 lbs body weight as the basis. (Thus if you weigh 200 lbs, increase the doses by 1/4; if you weigh 240 lbs, increase by 1/2, etc.)
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